The effect of ascorbic acid on infection chick-embryo ciliated tracheal organ cultures by coronavirus

Arch Virol. 1978;56(3):195-9. doi: 10.1007/BF01317848.

Abstract

Chick embryo tracheal organ cultures showed increased resistance to infection by a coronavirus after exposure to ascorbate, while chick respiratory epithelium and allantois-on-shell preparations showed no increase in resistance to infection by an influenza virus or a paramyxovirus.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Ascorbic Acid / pharmacology*
  • Chick Embryo
  • Coronaviridae / growth & development*
  • Infectious bronchitis virus / growth & development*
  • Influenza A virus / growth & development
  • Interferons / pharmacology
  • Newcastle disease virus / growth & development
  • Organ Culture Techniques
  • Trachea
  • Virus Replication / drug effects

Substances

  • Interferons
  • Ascorbic Acid